Identification | Back Directory | [Name]
Tos-PEG4-acid | [CAS]
1453117-42-4 | [Synonyms]
Tos-PEG4-acid Propanoic acid, 3-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]- | [Molecular Formula]
C16H24O8S | [MDL Number]
MFCD29052202 | [MOL File]
1453117-42-4.mol | [Molecular Weight]
376.42 |
Chemical Properties | Back Directory | [Boiling point ]
548.3±50.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
4.27±0.10(Predicted) | [color ]
Colorless to light yellow |
Hazard Information | Back Directory | [Description]
Tos-PEG4-acid is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. |
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