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ChemicalBook--->CAS DataBase List--->145148-39-6

145148-39-6

145148-39-6 Structure

145148-39-6 Structure
IdentificationBack Directory
[Name]

3-PiperidinaMine, N-[(2-Methoxyphenyl)Methyl]-2-phenyl-, (Hydrochloride) (1:2), (2S,3S)-
[CAS]

145148-39-6
[Synonyms]

CP 99,994 hydrochloride
(+)-CP-99994 dihydrochloride >=98% (HPLC)
(2S,3S)-3-(2-Methoxybenzylamino)-2-phenylpiperidine dihydrochloride
3-PiperidinaMine, N-[(2-Methoxyphenyl)Methyl]-2-phenyl-, (Hydrochloride) (1:2), (2S,3S)-
[Molecular Formula]

C19H25ClN2O
[MDL Number]

MFCD18782630
[MOL File]

145148-39-6.mol
[Molecular Weight]

332.87
Chemical PropertiesBack Directory
[Melting point ]

254-255 °C
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble15mg/mL, clear
[form ]

powder
[color ]

white to beige
[Water Solubility ]

H2O: 15mg/mL, clear
Safety DataBack Directory
[Hazard Codes ]

N
[Risk Statements ]

50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

CP 99994 Dihydrochloride (cas# 145148-39-6) is a useful research chemical.CP 99994 is a NK-??1 receptor antagonist.
[Biological Activity]

(+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets.''(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line.
[storage]

Desiccate at RT
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