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ChemicalBook--->CAS DataBase List--->1450644-28-6

1450644-28-6

1450644-28-6 Structure

1450644-28-6 Structure
IdentificationBack Directory
[Name]

TNU9056
[CAS]

1450644-28-6
[Synonyms]

TNU9056
Isothiazole, 5,5'-dithiobis-
1,2-Di(isothiazol-5-yl)disulfane
NU9056 1,2-Bis(isothiazol-5-yl)disulfane
TNU9056 1,2-Di(isothiazol-5-yl)disulfane
5-(1,2-thiazol-5-yldisulfanyl)-1,2-thiazole
[Molecular Formula]

C6H4N2S4
[MOL File]

1450644-28-6.mol
[Molecular Weight]

232.37
Chemical PropertiesBack Directory
[Boiling point ]

209.2±40.0 °C(Predicted)
[density ]

1.60±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

<10mg/ml in DMSO
[form ]

Liquid
[pka]

2.44±0.38(Predicted)
[color ]

Yellow to brown
Hazard InformationBack Directory
[Uses]

NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor. It inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Iy decreases proliferation of LNCaP cells and induces apoptosis via caspase activation.
[Biological Activity]

Cell permeable: yes''Primary Target
KAT5''Reversible: yes
[storage]

Store at -20°C
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