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ChemicalBook--->CAS DataBase List--->1442684-77-6

1442684-77-6

1442684-77-6 Structure

1442684-77-6 Structure
IdentificationBack Directory
[Name]

AM2394
[CAS]

1442684-77-6
[Synonyms]

AM2394
CS-2242
AM2394;AM 2394
N-[6'-(2-Hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methylurea
1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea
Urea, N-[6'-(2-hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methyl-
[Molecular Formula]

C22H25N5O4
[MDL Number]

MFCD30533320
[MOL File]

1442684-77-6.mol
[Molecular Weight]

423.46
Questions And AnswerBack Directory
[Uses]

AM 2394 is a structurally distinct glucokinase activator (GKA). AM-2394 activates GK with an EC50 of 60 nM.
Chemical PropertiesBack Directory
[Boiling point ]

588.8±50.0 °C(Predicted)
[density ]

1.266±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Room Temperature
[solubility ]

DMF: 1 mg/ml; DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.50 mg/ml
[form ]

A crystalline solid
[pka]

12.66±0.70(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[storage]

Store at -20°C
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