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ChemicalBook--->CAS DataBase List--->1428307-52-1

1428307-52-1

1428307-52-1 Structure

1428307-52-1 Structure
IdentificationBack Directory
[Name]

MRT-92 HCl salt
[CAS]

1428307-52-1
[Synonyms]

MRT-92 HCl salt
[Molecular Formula]

C33H35ClN4O5
[MOL File]

1428307-52-1.mol
[Molecular Weight]

603.12
Hazard InformationBack Directory
[Description]

MRT-92 is a potent and selective Smoothened (Smo) receptor inhibitor. MRT-92 displays subnanomolar antagonist activity against Smo in various Hh cell-based assays. MRT-92 inhibits rodent cerebellar granule cell proliferation induced by Hh pathway activation through pharmacologic (half maximal inhibitory concentration [IC50] = 0.4 nM) or genetic manipulation. Smo is the target of anticancer drugs that bind to a long and narrow cavity in the 7-transmembrane (7TM) domain.
1428307-52-1 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135 , +8613564774135
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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