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ChemicalBook--->CAS DataBase List--->1421372-66-8

1421372-66-8

1421372-66-8 Structure

1421372-66-8 Structure
IdentificationBack Directory
[Name]

Mutated EGFR-IN-1
[CAS]

1421372-66-8
[Synonyms]

OMT-3
CS-1173
HY-78869
AZD9291 3
AZD9291 N-2
AZD9291 int-5
AZD9291 INT1 N-2
Mutated EGFR-IN-1
AZD9291DA HCl salt
AZD91 intermediate
Osimertinib analog
AZD9291 intermediate
AZD9291 Intermediate1
Osimertinib Impurity 5
AZD9291 intermediate 4
AZD9291 intermediates 3
Mutated EGFR inhibitor 1
Osimertinib intermediate
Mereletinib Intermediates
Osimertinib Intermediate 3
Mutated EGFR-IN-1 (Osimertinib analog)
N1-(2-(Dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)b
N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-m-ethyl-1H-indol-3-yl)-2-pyrimidi-nyl]-1,2,
N1-(2-dimethylaminoethyl)-5-methoxy-N1-methyl-N4-[4-(1-methylindol-3-yl)pyrimidin-2-yl]benzene-1,2,4-triamine
N1-(2-(dimethylamino)ethyl)-5-methoxy-N1-methyl-N4-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)benzene-1,2,4-triamine
N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]benzene-1,2,4-triamine
N1-[2-(Dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-1,2,4-benzenetriamine
1,2,4-Benzenetriamine, N1-[2-(dimethylamino)ethyl]-5-methoxy-N1-methyl-N4-[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]-
N-(2-dimethylamino-ethyl)-2-methoxy-n-methyl-n-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-5-Amino-benzene-1,4-diamine
[Molecular Formula]

C25H31N7O
[MDL Number]

MFCD28167800
[MOL File]

1421372-66-8.mol
[Molecular Weight]

445.56
Chemical PropertiesBack Directory
[Boiling point ]

676.5±65.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: ≥ 75 mg/mL (168.33 mM)
[form ]

Powder
[pka]

9.07±0.28(Predicted)
[InChIKey]

HTNTZPBKKCORTP-UHFFFAOYSA-N
[SMILES]

C1(N(CCN(C)C)C)=CC(OC)=C(NC2=NC=CC(C3C4=C(N(C)C=3)C=CC=C4)=N2)C=C1N
Hazard InformationBack Directory
[Uses]

N1-?[2-?(Dimethylamino)?ethyl]?-?5-?methoxy-?N1-?methyl-?N4-?[4-?(1-?methyl-?1H-?indol-?3-?yl)?-?2-?pyrimidinyl]?-?1,?2,?4-?benzenetriamine can be involved as reactant/reagent in "Schizophrenic" self-assembly of dual thermoresponsive block copolymers bearing a zwitterionic and a non-ionic hydrophilic block.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Mutated EGFR-IN-1(1421372-66-8)1HNMR
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Tags:1421372-66-8 Related Product Information
1421373-66-1 1421373-65-0 1421372-94-2 1421372-67-9

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