| Identification | Back Directory | [Name]
MK-8318 | [CAS]
1416581-40-2 | [Synonyms]
MK-8318
Butanoic acid, 4-[cyclopropyl[(3aS,9R,9aR)-7-fluoro-2,3,3a,4,9,9a-hexahydro-4-[4-(trifluoromethoxy)benzoyl]-1H-cyclopenta[b]quinolin-9-yl]amino]-4-oxo- | [Molecular Formula]
C27H26F4N2O5 | [MDL Number]
MFCD31807606 | [MOL File]
1416581-40-2.mol | [Molecular Weight]
534.5 |
| Hazard Information | Back Directory | [Description]
MK-8318 is potent and selective CRTh2 antagonist activity and a favorable PK profile suitable for once daily oral dosing for potential treatment of asthma. MK-8318 showed good in vitro and in vivo activity (Ki = 2.3 nM; IC50 cAMP = 8 nM). | [storage]
Store at -20°C |
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