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ChemicalBook--->CAS DataBase List--->141450-48-8

141450-48-8

141450-48-8 Structure

141450-48-8 Structure
IdentificationBack Directory
[Name]

E-7010 monohydrochloride
[CAS]

141450-48-8
[Synonyms]

ABT-751 hydrochloride
E-7010 monohydrochloride
ABT-751 monohydrochloride
ABT-751 hydrochloride >=98% (HPLC)
N-[2-[(4-Hydroxyphenyl)aMino]-3-pyridyl]-4-MethoxybenzenesulfonaMide hydrochloride
N-{2-[(4-hydroxyphenyl)aMino]pyridin-3-yl}-4-MethoxybenzenesulfonaMide hydrochloride
N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide monohydrochloride
BenzenesulfonaMide, N-[2-[(4-hydroxyphenyl)aMino]-3-pyridinyl]-4-Methoxy-, Monohydrochloride
[Molecular Formula]

C18H18ClN3O4S
[MDL Number]

MFCD19440802
[MOL File]

141450-48-8.mol
[Molecular Weight]

407.871
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥15mg/mL
[form ]

powder
[color ]

pink to purple
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22-36/37/38
[Safety Statements ]

26
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

ABT-751 is an orally bioavailable vascular disrupting agent (VDA) with a broad spectrum of antitumor activity. It binds to the colchicine binding site on β-tubulin and inhibits polymerization of microtubules.''ABT-751a sulfonamide antimitotic agentis under clinical trials to tre at patients with various malignancies including refractory hematologic malignanciesnon-small cell lung cancer (NSCLC)and colon cancer.
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