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ChemicalBook--->CAS DataBase List--->141283-87-6

141283-87-6

141283-87-6 Structure

141283-87-6 Structure
IdentificationBack Directory
[Name]

IS 741
[CAS]

141283-87-6
[Synonyms]

IS 741
Fuzapladib
Fuzapladib （IS-741）
IS-741 (Fuzapladib
Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-
[Molecular Formula]

C15H20F3N3O3S
[MOL File]

141283-87-6.mol
[Molecular Weight]

379.4
Chemical PropertiesBack Directory
[density ]

1.411±0.06 g/cm3(Predicted)
[storage temp. ]

-10 to -25°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

Solid
[pka]

5.41±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

Fuzapladib (IS-741) is a cell penetrant and potent phospholipase A2 (PLA2) inhibitor. Fuzapladib decelerate the progression of pancreatic fibrosis through monocyte infiltration in dogs.
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