Identification | Back Directory | [Name]
[2H3]-N6-Methyladenosine | [CAS]
139896-43-8 | [Synonyms]
[2H3]-N6-Methyladenosine N6-trideuteriomethyl-adenosine | [Molecular Formula]
C11H15N5O4 | [MOL File]
139896-43-8.mol | [Molecular Weight]
281.27 |
Hazard Information | Back Directory | [Uses]
Isotope labelled N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine. |
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