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ChemicalBook--->CAS DataBase List--->1396841-57-8

1396841-57-8

1396841-57-8 Structure

1396841-57-8 Structure
IdentificationBack Directory
[Name]

RGFP966
[CAS]

1396841-57-8
[Synonyms]

CS-1872
(E,E)-RGFP966
RGFP966 Racemate
(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide
(E,E)-N-(2-Amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide
2-Propenamide (N-(2-amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl]
2-Propenamide, N-(2-amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl]-, (2E)-
RGFP966 (E)-N-(2-Amino-4-fluorophenyl)-3-[1-[(E)-3-phenylprop-2-enyl]pyrazol-4-yl]prop-2-enamide
[Molecular Formula]

C21H19FN4O
[MDL Number]

MFCD26960954
[MOL File]

1396841-57-8.mol
[Molecular Weight]

362.4
Chemical PropertiesBack Directory
[Boiling point ]

630.4±55.0 °C(Predicted)
[density ]

1.19±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 20mg/mL, clear
[form ]

powder
[pka]

11.58±0.70(Predicted)
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H332
[Precautionary statements ]

P280
Hazard InformationBack Directory
[Uses]

RGFP966 is a histone deacetylase 3 (HDAC3) inhibitor.
[Definition]

ChEBI: N-(2-amino-4-fluorophenyl)-3-[1-(3-phenylprop-2-enyl)-4-pyrazolyl]-2-propenamide is an aromatic amide and an aromatic amine.
[Biochem/physiol Actions]

RGFP966 changes signal-specific primary auditory cortical plasticity. It is highly effective in cardiomyopathy-associated pathologies.
Spectrum DetailBack Directory
[Spectrum Detail]

RGFP966(1396841-57-8)1HNMR
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