| Identification | Back Directory | [Name]
NOR-3 | [CAS]
138472-01-2 | [Synonyms]
FK409
NOR-3
4-ETHYL2-E-(HYDROXYIMINO)-5-NITRO-3E-HEXENAMIDE
3-Hexenamide, 4-ethyl-2-(hydroxyimino)-5-nitro-, (2E,3E)-
(+/-)-(E)-ETHYL-2-[(E)-HYDROXYIMINO]-5-NITRO-3-HEXENEAMIDE
(+/-)-(E)-4-ETHYL-2-[(E)-HYDROXYIMINO]-5-NITRO-3-HEXENAMIDE
(+/-)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexeneamide (NOR 3) | [Molecular Formula]
C8H13N3O4 | [MDL Number]
MFCD00270892 | [MOL File]
138472-01-2.mol | [Molecular Weight]
215.21 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
DMF: >34 mg/ml; DMSO: >20 mg/ml; Ethanol: >36 mg/ml; PBS pH 7.2: >2.2 mg/ml | [form ]
White to off-white crystalline solid. |
| Hazard Information | Back Directory | [Uses]
FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37°C. The IC50 for the inhibition of platelet aggregation is 4.9 μM. | [Uses]
NOR-3 is a cell-permeable NO donor. | [Biological Activity]
Activates intracellular guanylyl cyclase. | [storage]
Store at -20°C |
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