Identification | Back Directory | [Name]
1H-Indole, 5-bromo-2-[4-methoxy-5-(2H-pyrrol-2-ylidenemethyl)-1H-pyrrol-2-yl]- | [CAS]
1383727-17-0 | [Synonyms]
SC2001 SC-2001 SC 2001 1H-Indole, 5-bromo-2-[4-methoxy-5-(2H-pyrrol-2-ylidenemethyl)-1H-pyrrol-2-yl]- | [Molecular Formula]
C18H14BrN3O | [MOL File]
1383727-17-0.mol | [Molecular Weight]
368.23 |
Hazard Information | Back Directory | [Description]
SC-2001 is a MCL-1 inhibitor. SC-2001 is an Obatoclax analog that inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. SC-2001 overcomes STAT3-mediated sorafenib resistance through RFX-1/SHP-1 activation in hepatocellular carcinoma. |
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