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ChemicalBook--->CAS DataBase List--->1374006-96-8

1374006-96-8

1374006-96-8 Structure

1374006-96-8 Structure
IdentificationBack Directory
[Name]

ERDRP-0519
[CAS]

1374006-96-8
[Synonyms]

[Molecular Formula]

C23H30F3N5O4S
[MDL Number]

MFCD34166663
[MOL File]

1374006-96-8.mol
[Molecular Weight]

529.58
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (188.83 mM; Need ultrasonic)
[form ]

Solid
[pka]

12.28±0.70(Predicted)
[color ]

Off-White
Hazard InformationBack Directory
[Uses]

ERDRP-0519 is a novel orally available polymerase inhibitor, showing efficacy against a lethal morbillivirus Infection in a large animal model.
[in vivo]

A single-dose pharmacokinetic (PK) study is performed in squirrel monkeys by oral (intragastric) delivery of ERDRP-0519 (50 mg/kg) and blood sampling at seven predefined time points after dosing. Serum concentrations peak ~2 h post-administration (Cmax=3.27 μM)[3].
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