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ChemicalBook--->CAS DataBase List--->136451-98-4

136451-98-4

136451-98-4 Structure

136451-98-4 Structure
IdentificationBack Directory
[Name]

A 73209
[CAS]

136451-98-4
[Synonyms]

A 73209
1-(3',4'-Bis(hydroxymethyl)-2'-oxetanyl)-5-methyluracil
1-[(2R,3R,4S)-3,4-bis(hydroxymethyl)oxetan-2-yl]-5-methylpyrimidine-2,4-dione
2,4(1H,3H)-Pyrimidinedione, 1-((2R,3R,4S)-3,4-bis(hydroxymethyl)-2-oxetanyl)-5-methyl-
2,4(1H,3H)-Pyrimidinedione, 1-(3,4-bis(hydroxymethyl)-2-oxetanyl)-5-methyl-, (2R-(2alpha,3beta,4alpha))-
[Molecular Formula]

C10H14N2O5
[MOL File]

136451-98-4.mol
[Molecular Weight]

242.23
Chemical PropertiesBack Directory
[density ]

1.419±0.06 g/cm3(Predicted)
[pka]

9.55±0.10(Predicted)
Hazard InformationBack Directory
[Description]

A 73209 is a nucleoside analog of the oxetanocin family. It originates from a class of compounds that inhibit viral DNA synthesis. A-73209 appears to be a potent and selective agent against varicella-zoster virus and herpes simplex virus infections.
[Uses]

A-73209 is an orally active and potent antivirus agent against VZV, HSV-1, and HSV-2. A-73209 is an Oxetanocin derivative and can be utilized in antivirus research[1].
[References]

[1] Alder J, et al. Efficacy of A-73209, a potent orally active agent against VZV and HSV infections. Antiviral Res. 1994 Feb;23(2):93-105. DOI:10.1016/0166-3542(94)90037-x
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