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ChemicalBook--->CAS DataBase List--->136449-85-9

136449-85-9

136449-85-9 Structure

136449-85-9 Structure
IdentificationBack Directory
[Name]

NPC-15437 DIHYDROCHLORIDE
[CAS]

136449-85-9
[Synonyms]

NPC-15437
NPC154372HCl
Npc1537 dihydrochloride
NPC-15437 DIHYDROCHLORIDE
NPC-15437 hydrate dihydrochloride
2,6-Diamino-N-[(1-tridecanoyl-2-piperidinyl)methyl]hexanamide
Hexanamide, 2,6-diamino-N-[[1-(1-oxotridecyl)-2-piperidinyl]methyl]-, (2S)-
S-2,6-DIAMINO-N-([1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL)HEXANAMIDE DIHYDROCHLORIDE
S-2,6-DIAMINO-N-[[1'-(1''OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
S-2,6-DIAMINO-N-[[1'-(1'-OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
(2S)-2,6-DIAMINO-N-[[1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
[Molecular Formula]

C25H50N4O2
[MDL Number]

MFCD00210207
[MOL File]

136449-85-9.mol
[Molecular Weight]

438.69
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: ≥36 mg/mL
[form ]

solid
[color ]

white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

Highly selective, competitive and reversible inhibitor of protein kinase C (IC 50 = 19 mM); interacts at the regulatory domain of the enzyme. May modulate P-glycoprotein in tumor cells in vitro via inhibiton of PKC. Centrally active following systemic administration in vivo .
[storage]

+4°C
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