| Identification | Back Directory | [Name]
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine | [CAS]
1363380-51-1 | [Synonyms]
arotrectinib CNPP Impurity
5-Chloro-3-nitropyrazolo[...
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidin
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-chloro-3-nitropyrazole [1,5-a] pyrimidine
Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-nitro-
Larotrectinib Impurity 1（Larotrectinib CNPP Impurity） | [Molecular Formula]
C6H3ClN4O2 | [MDL Number]
MFCD22415211 | [MOL File]
1363380-51-1.mol | [Molecular Weight]
198.567 |
| Chemical Properties | Back Directory | [Melting point ]
163 - 165°C | [density ]
1.85±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Chloroform (Slightly, Heated), DMSO (Slightly) | [form ]
Solid | [pka]
-3.59±0.40(Predicted) | [color ]
Purple |
| Hazard Information | Back Directory | [Uses]
5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer. |
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