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ChemicalBook--->CAS DataBase List--->1358027-80-1

1358027-80-1

1358027-80-1 Structure

1358027-80-1 Structure
IdentificationBack Directory
[Name]

PH 797804
[CAS]

1358027-80-1
[Synonyms]

(-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
Benzamide, 3-[3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethyl-, (3S)-
[Molecular Formula]

C22H19BrF2N2O3
[MDL Number]

MFCD18251426
[MOL File]

1358027-80-1.mol
[Molecular Weight]

477.3
Chemical PropertiesBack Directory
[solubility ]

Soluble to 50 mM in DMSO
Hazard InformationBack Directory
[Uses]

(S)-(-)-PH-797804 is an atropisomer of PH-797804 (P399155) which is a novel N-phenylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase known to exerts anti-inflammatory properties.
[Definition]

ChEBI: PH 797804 is a member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine. It has a role as an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor and an anti-inflammatory agent. It is a member of benzamides, an organofluorine compound, a pyridone, an organobromine compound and an aromatic ether.
[storage]

Store at -20°C
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