| Identification | Back Directory | [Name]
Benserazide Hydrochloride impurity C | [CAS]
1353749-74-2 | [Synonyms]
Benserazide EP Impurity C HCl
CSRM617 hydrochloride
(CSRM-617)
Benserazide Hydrochloride impurity C
(2,3,4-Trihydroxyphenyl)methylene]hydrazide-serine Hydrochloride | [EINECS(EC#)]
940-411-0 | [Molecular Formula]
C10H14ClN3O5 | [MOL File]
1353749-74-2.mol | [Molecular Weight]
291.69 |
| Chemical Properties | Back Directory | [Melting point ]
>177°C (dec.) | [density ]
1.68g/cm3 at 21℃ | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Water (Slightly, Sonicated) | [form ]
Solid | [color ]
Off-White to Pale Beige | [LogP]
1 at 40℃ and pH6.5 |
| Hazard Information | Back Directory | [Uses]
[(2,3,4-Trihydroxyphenyl)methylene]hydrazide-serine Hydrochloride is an impurity of Benserazide (B120505) which is a drug which in combination with dopamine precursor Levodopa (D533751) is used in the management of Parkinson’s disease. | [in vivo]
CSRM617 (50 mg/kg; p.o.; daily, for 20 d) inhibits tumor growth in SCID mice with 22Rv1 xenograft[1]. | Animal Model: | SCID mice with 22Rv1 xenograft[1] | | Dosage: | 50 mg/kg | | Administration: | Oral administration; daily, for 20 days | | Result: | Elicited a significant reduction in the onset and growth of diffuse metastases. |
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| Company Name: |
TOSUN PHARM
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| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
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