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ChemicalBook--->CAS DataBase List--->1352750-34-5

1352750-34-5

1352750-34-5 Structure

1352750-34-5 Structure
IdentificationBack Directory
[Name]

WSP-1
[CAS]

1352750-34-5
[Synonyms]

WSP-1
Washington State Probe-1
WSP-1 *CAS 1352750-34-5*
3'-methoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl 2-(pyridin-2-yldisulfanyl)benzoate
Benzoic acid, 2-(2-pyridinyldithio)-, 6'-methoxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester
[Molecular Formula]

C33H21NO6S2
[MDL Number]

MFCD31010433
[MOL File]

1352750-34-5.mol
[Molecular Weight]

591.65
Chemical PropertiesBack Directory
[Boiling point ]

769.9±60.0 °C(Predicted)
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C, protect from light
[solubility ]

DMF: 20 mg/ml; DMSO: 2 mg/ml
[form ]

A crystalline solid
[pka]

1.39±0.19(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.1
[References]

1. Liu, C., Pan, J., Li, S., et al. Capture and visualization of hydrogen sulfide via a fluorescent probe Angew. Chem. Int. Ed. Engl. 50(44),10327-10329(2011).
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