| Identification | Back Directory | [Name]
1-Piperidinecarboxylic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester | [CAS]
1352011-38-1 | [Synonyms]
SAR127303
SAR-127303
SAR 127303
1-Piperidinecarboxylic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester | [Molecular Formula]
C16H17ClF6N2O4S | [MOL File]
1352011-38-1.mol | [Molecular Weight]
482.83 |
| Hazard Information | Back Directory | [Description]
SAR127303 is a potent covalent MAGL inhibitor. SAR127303 behaves as a selective and competitive inhibitor of mouse and human MAGL, which potently elevates hippocampal levels of 2-AG in mice. In vivo, SAR127303 produces antinociceptive effects in assays of inflammatory and visceral pain. |
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