| Identification | Back Directory | [Name]
OBAA | [CAS]
134531-42-3 | [Synonyms]
OBAA
3-(4-OCTADECYL)-BENZOYLACRYLIC ACID
4-(4-OCTADECYLPHENYL)-4-OXOBUTENOIC ACID
4-(4-octadecylphenyl)-4-oxo-2-Butenoic acid
2-Butenoic acid, 4-(4-octadecylphenyl)-4-oxo- | [Molecular Formula]
C28H44O3 | [MDL Number]
MFCD00211140 | [MOL File]
134531-42-3.mol | [Molecular Weight]
428.65 |
| Chemical Properties | Back Directory | [Boiling point ]
558.6±50.0 °C(Predicted) | [density ]
0.976±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
DMSO: ≥5mg/mL at 60°C | [form ]
powder | [pka]
3.20±0.10(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
OBAA is a phospholipase A2 and HSP90 inhibitor. | [Biological Activity]
A potent inhibitor of phospholipase A 2 (IC 50 = 70 nM). Reduces bronchospasm in guinea pigs in vivo . | [in vivo]
The immunologically induced bronchospasm in guinea pigs is significantly and dose-dependently inhibited by OBAA (2.5-7 mg/kg i.v.)[3]. | [IC 50]
PLA2: 70 nM (IC50) |
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Energy Chemical
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Merck KGaA
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