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ChemicalBook--->CAS DataBase List--->1336890-05-1

1336890-05-1

1336890-05-1 Structure

1336890-05-1 Structure
IdentificationBack Directory
[Name]

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)
[CAS]

1336890-05-1
[Synonyms]

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)
1H-Benzimidazol-6-amine, 2-(difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-methoxy-
[Molecular Formula]

C20H24F2N8O3
[MOL File]

1336890-05-1.mol
[Molecular Weight]

462.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 46 mg/mL (99.47 mM);Ethanol: Insoluble
[Water Solubility ]

Water: Insoluble
Hazard InformationBack Directory
[Biological Activity]

Compound 10w, a substituted pyrazolo [1,5-a] pyrimidine amide derivative, shows good anticancer activity against HeLa cell line, with IC50 of less than 10 μM against HeLa cell.
[storage]

Store at -20°C
[References]

[1] Kumar AKA, et al. Medicinal Chemistry Research. 2017; 26, 714-744.
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