Identification | Back Directory | [Name]
Spironolactone EP Impurity A | [CAS]
132458-33-4 | [Synonyms]
Δ20-Spironolactone Spiranolactone IMP A Spironolactone Impurity A Spiranolactone Impurity A Spironolactone EP Impurity A 20,21-Dehydro Spironolactone Spironolactone EP Impurity A (Delta-20-Spironolactone) Spironolactone Impurity 1(Spironolactone EP Impurity A) Pregna-4,20-diene-21-carboxylic acid, 7-(acetylthio)-17-hydroxy-3-oxo-, γ-lactone, (7α,17α)- (9CI) S-[(2′R)-3,5′-dioxo-5′H-spiro[androst-4-ene-17,2′-furan]-7α-yl] ethanethioate (Δ20-spironolactone) Spironolactone Related Compound B ((2''R)-7alpha-(Acetylthio)-5''H-spiro[androst-4-ene-17,2''-furan]-3 (1619028) S-((7S,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl)ethanethioate S-((2'R,7R,8R,9S,10R,13S,14S)-10,13-Dimethyl-3,5'-dioxo-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-5'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl) ethanethioate (Spironolactone Impurity) | [Molecular Formula]
C24H30O4S | [MOL File]
132458-33-4.mol | [Molecular Weight]
414.56 |
Chemical Properties | Back Directory | [Melting point ]
205-208°C | [Boiling point ]
603.0±55.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
20,21-Dehydro Spironolactone (Spironolactone EP Impurity A) is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome. |
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BOC Sciences
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BOC Sciences
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TOSUN PHARM
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Energy Chemical
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