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ChemicalBook--->CAS DataBase List--->1316059-00-3

1316059-00-3

1316059-00-3 Structure

1316059-00-3 Structure
IdentificationBack Directory
[Name]

3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
[CAS]

1316059-00-3
[Synonyms]

159344
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Benzenesulfonamide, 3-[[6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino]-4-(ethylsulfonyl)-N-methyl-
[Molecular Formula]

C18H19ClN6O4S2
[MDL Number]

MFCD29919171
[MOL File]

1316059-00-3.mol
[Molecular Weight]

482.96
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 250 mg/mL (517.64 mM; Need ultrasonic)
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Biological Activity]

GSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].
[storage]

Store at -20°C
[References]

[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.
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