Identification | Back Directory | [Name]
(S)-3-(4-((5-((2,3-DIHYDROSPIRO[INDENE-1,4-PIPERIDIN]-1-YL)METHYL)THIOPHEN-2-YL)METHOXY)PHENYL)HEX-4-YNOIC ACID | [CAS]
1309435-78-6 | [Synonyms]
(S)-3-(4-((5-((2,3-DIHYDROSPIRO[INDENE-1,4-PIPERIDIN]-1-YL)METHYL)THIOPHEN-2-YL)METHOXY)PHENYL)HEX-4-YNOIC ACID | [Molecular Formula]
C31H34NO3S | [MDL Number]
MFCD30829538 | [MOL File]
1309435-78-6.mol | [Molecular Weight]
500.672 |
Hazard Information | Back Directory | [Description]
LY2922083 is a Potent and Selective GPR40 Agonist for the Treatment of Type 2 Diabetes Mellitus. LY2922083 demonstrated potent, efficacious and durable dose dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion during preclinical testing. The G protein-coupled receptor 40 (GPR40) also known as Free Fatty Acid Receptor 1 (FFAR1) is highly expressed in pancreatic, islet beta-cells and responds to endogenous fatty acids resulting in amplification of insulin secretion only in the presence of elevated glucose levels. |
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Company Name: |
AstaTech, Inc
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Tel: |
(215) 785 3197 |
Website: |
www.astatechinc.com |
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