| Identification | Back Directory | [Name]
15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER | [CAS]
130273-87-9 | [Synonyms]
17-phenyl trinor PGF2α-iPr
JGZRPRSJSQLFBO-DYZSFVSISA-N
15(R)-Bimatoprost isopropyl ester
15-epi Bimatoprost isopropyl ester
17-phenyl trinor PGF2α isopropyl ester
Bimatoprost Acid 15-Epi Isopropyl Ester
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester
15(R)-17-PHENYL TRINOR PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER
BIMATOPROST ISOPROPYL ESTER/7-[(1R,2R,3R,5S)-3,5-DIHYDROXY-2-[(1E,3R)-3-HYDROXY-5-PHENYL-1-PENTEN-1-
9ALPHA,11ALPHA,15R-TRIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID, ISOPROPYL ESTER
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl)hept-5-enoate
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-, 1-methylethyl ester, (5Z)-
Bimatoprost Isopropyl Ester/7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-Hydroxy-5-Phenyl-1-Penten-1-Yl]Cyclopentyl]-(5Z)-5-Heptenoic Acid 1-Methylethyl Ester | [Molecular Formula]
C26H38O5 | [MDL Number]
MFCD05863953 | [MOL File]
130273-87-9.mol | [Molecular Weight]
430.58 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF:30.0(Max Conc. mg/mL);69.67(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);69.67(Max Conc. mM)
PBS (pH 7.2):1.0(Max Conc. mg/mL);2.32(Max Conc. mM) |
| Hazard Information | Back Directory | [Description]
15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys. | [storage]
Store at -20°C |
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