| Identification | Back Directory | [Name]
ClarithroMycin EP IMpurity F | [CAS]
128940-83-0 | [Synonyms]
12-O-Methyl ClarithroMycin
6,12-Di-O-MethylerythroMycin
ClarithroMycin EP IMpurity F
6,12-Di-O-MethylerythroMycin A
Erythromycin, 6,12-di-O-methyl-
12-O-Methyl Clarithromycin (~90%)
Clarithromycin Impurity 6(Clarithromycin EP Impurity F)
Clarithromycin EP Impurity F/12-O-Methyl Clarithromycin | [Molecular Formula]
C39H71NO13 | [MOL File]
128940-83-0.mol | [Molecular Weight]
761.98 |
| Chemical Properties | Back Directory | [Melting point ]
112-115 °C | [Boiling point ]
806.1±65.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.19±0.70(Predicted) | [color ]
White to Light Beige |
| Hazard Information | Back Directory | [Uses]
12-O-Methyl Clarithromycin (Clarithromycin EP Impurity F) is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. | [Uses]
12-O-Methyl Clarithromycin is a methylated impurity of the semi-synthetic macrolide antibiotic Clarithromycin (C559750). 12-O-Methyl Clarithromycin was shown to inhibit uptake of Clarithromycin into the lung cells. |
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