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ChemicalBook--->CAS DataBase List--->1268494-46-7

1268494-46-7

1268494-46-7 Structure

1268494-46-7 Structure
IdentificationBack Directory
[Name]

Tigecycline (open C-ring D-ring) Quinone
[CAS]

1268494-46-7
[Synonyms]

Tigecycline Impurity 4
Tigecycline Impurity 9
Tigecycline USP Impurity F
Tigecycline Quinone Impurity
Tigecycline Quinone Analogue
(S)-4-((6-(2-(tert-butylamino)acetamido)
Tigecycline (open C-ring D-ring) Quinone
Tigecycline Impurity 2(Tigecycline quinone analog)
Tigecycline (open C-ring D-ring) Quinone (Technical Grade) DISCONTINUED. Please see T440035
4-[[(2S)-6-[[2-(tert-butylamino)acetyl]amino]-8-(dimethylamino)-5-hydroxy-4-oxo-2,3-dihydro-1H-naphthalen-2-yl]methyl]-2,5-dihydroxy-3,6-dioxocyclohexa-1,4-diene-1-carboxamide
1,4-Cyclohexadiene-1-carboxamide, 4-[[(2S)-8-(dimethylamino)-6-[[2-[(1,1-dimethylethyl)amino]acetyl]amino]-1,2,3,4-tetrahydro-5-hydroxy-4-oxo-2-naphthalenyl]methyl]-2,5-dihydroxy-3,6-dioxo-
[Molecular Formula]

C26H32N4O8
[MOL File]

1268494-46-7.mol
[Molecular Weight]

528.55
Chemical PropertiesBack Directory
[Melting point ]

>148°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Dark Red
Hazard InformationBack Directory
[Uses]

Tigecycline (open C-ring D-ring) quinone is an impurity of Tigecycline (T440015), one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline.
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