Chemical Properties | Back Directory | [solubility ]
Dissolve 1.0 g in 10 mL of water R. The solution is clear (2.2.1) and not more intensely coloured than intensity 5 of the range of reference solutions of the most appropriate colour (2.2.2, Method II) |
Hazard Information | Back Directory | [Uses]
Innohep (Pharmion). | [Clinical Use]
Peri- and postoperative surgical thromboprophylaxis Treatment of DVT and pulmonary embolism Prevention of thrombus formation in extracorporeal circulation during HD | [Drug interactions]
Potentially hazardous interactions with other drugs
Analgesics: increased risk of bleeding with NSAIDs
- avoid concomitant use with IV diclofenac;
increased risk of haemorrhage with ketorolac - avoid
concomitant use.
Nitrates: anticoagulant effect reduced by infusions of
glyceryl trinitrate.
Use with care in patients receiving oral
anticoagulants, platelet aggregation inhibitors, aspirin
or dextran. | [Metabolism]
Low molecular weight heparins are partially metabolised by desulphation and depolymerisation. The kidneys are the major site of tinzaparin excretion (approximately 70 % based on animal studies). |
|
Company Name: |
EDQM
|
Tel: |
+ 33 (0) 3 88 41 30 30 |
Website: |
www.edqm.eu |
|