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ChemicalBook--->CAS DataBase List--->1263166-93-3

1263166-93-3

1263166-93-3 Structure

1263166-93-3 Structure
IdentificationBack Directory
[Name]

N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane
[CAS]

1263166-93-3
[Synonyms]

BCN-amine
BCN-POE3-NH2
BCN-PEG3-NH2
CAS_1263166-93-3
BCN-endo-PEG2-NH2
endo-BCN-PEG2-NH2
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylMethyloxycarbonyl-1,8-diaMino-3,6-dioxaoctane
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane >
(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate
Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, (1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane
N-[(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl]-1,8-diamino-3,6-dioxaoctane for Copper-free Click Chemistry
[Molecular Formula]

C17H28N2O4
[MDL Number]

MFCD19705418
[MOL File]

1263166-93-3.mol
[Molecular Weight]

324.415
Chemical PropertiesBack Directory
[Boiling point ]

487.1±30.0 °C(Predicted)
[density ]

1.14±0.1 g/cm3(Predicted)
[storage temp. ]

?20°C
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[form ]

clear liquid
[pka]

12.05±0.46(Predicted)
[color ]

Light yellow to Yellow to Orange
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

2924.29.9500
Hazard InformationBack Directory
[Description]

endo-BCN-PEG2-amine is a heterobifunctional PEG linker containing a BCN and an amine group. The BCN group can react with azide-tagged molecules. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
[Uses]

Amine functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.
[reaction suitability]

reaction type: click chemistry
reagent type: linker
[IC 50]

PEGs
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