| Identification | Back Directory | [Name]
CHOLESTANE-3B,5A,6B-TRIOL | [CAS]
1253-84-5 | [Synonyms]
NSC 18178
NSC 124751
CHOLESTANTRIOL
Cholesta-3β,5α,6β-triol
CHOLESTANE-3B,5A,6B-TRIOL
5α,6β-Dihydroxycholestanol
5α-Cholestane-3β,5,6β-triol
5α-Cholestane-3β,5α,6β-triol
5β-Cholestane-3β,5α,6β-triol
Cholestane-3B,5ALPHA,6B-triol
3β,5α,6β-Trihydroxycholestane
3β-Hydroxycholestane-5α,6β-diol
(3β,5α,6β)-Cholestane-3,5,6-triol
3beta,5alpha,6beta-Cholestanetriol
5-alpha,6-beta-dihydroxycholestanol
Cholestane-3,5,6-triol, (3b,5a,6b)-
cholestane-3-beta,5-alpha,6-beta-triol
5-alpha-cholestane-3-beta,5,6-beta-triol
6-triol,(3-beta,5-alpha,6-beta)-cholestane-5
Cholestane-3,5,6-triol, (3.beta.,5.alpha.,6.beta.)-
(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,5,6-triol
(3S,5R,6R,8S,10R,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol
(3S,5R,6R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthrene-3,5,6-triol | [Molecular Formula]
C27H48O3 | [MDL Number]
MFCD00021171 | [MOL File]
1253-84-5.mol | [Molecular Weight]
420.668 |
| Chemical Properties | Back Directory | [Melting point ]
226-231°C | [Boiling point ]
515.7±40.0 °C(Predicted) | [density ]
1.065±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Methanol (Slightly) | [form ]
Solid | [pka]
14.26±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Cholesterol analog. Useful for treatment of hyperlipemia, arteriosclerosis, diabetes, obesity. | [Definition]
ChEBI: 5alpha-cholestane-3beta,5,6beta-triol is a 3beta-hydroxy steroid, a 6beta-hydroxy steroid and a 5alpha-hydroxy steroid. It derives from a hydride of a 5alpha-cholestane. | [Biological Activity]
5α,6β-dihydroxycholestanol (5α,6α-diOH-Chol) or cholestan-3β,5α,6β-triol (C-triol) levels are elevated along with 7-ketocholesterol in Niemann-Pick type C (NP-C) disease and is a key biomarkers for detection. It exhibits neuroprotective functionality during central nervous system (CNS) ischemia. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22-68/20/21/22 | [Safety Statements ]
36 | [WGK Germany ]
1
| [RTECS ]
FZ6275000
| [Toxicity]
mouse,LD50,intraperitoneal,130mg/kg (130mg/kg),BEHAVIORAL: MUSCLE WEAKNESSGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Japanese Journal of Pharmacology. Vol. 17, Pg. 340, 1967. |
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Alfa Chemistry
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1-516-6625404 |
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https://www.alfa-chemistry.com |
| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
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