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ChemicalBook--->CAS DataBase List--->1250963-36-0

1250963-36-0

1250963-36-0 Structure

1250963-36-0 Structure
IdentificationBack Directory
[Name]

CLR1501
[CAS]

1250963-36-0
[Synonyms]

CLR1501
18-(4-(5,5-difluoro-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)phenyl)octadecyl (2-(trimethylammonio)ethyl) phosphat
5,5-Difluoro-10-(4-(18-((oxido(2-(trimethylammonio)ethoxy)phosphoryl)oxy)octadecyl)phenyl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide
[Molecular Formula]

C38H59BF2N3O3P
[MDL Number]

MFCD30543750
[MOL File]

1250963-36-0.mol
[Molecular Weight]

685.675
Chemical PropertiesBack Directory
[form ]

Oil
[color ]

Brown to reddish brown
Hazard InformationBack Directory
[Description]

CLR1501 is a fluorescent cancer-selective alkylphosphocholine analog for intraoperative glioma detection.
[Uses]

CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound[1][2].
[References]

[1] Weichert JP, et al. Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75. DOI:10.1126/scitranslmed.3007646
[2] Swanson KI, et al. Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection. Neurosurgery. 2015 Feb;76(2):115-23; discussion 123-4. DOI:10.1227/NEU.0000000000000622
[3] Deming DA, Maher ME, Leystra AA, et al. Phospholipid ether analogs for the detection of colorectal tumors. PLoS One. 2014;9(10):e109668. DOI:10.1371/journal.pone.0109668
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