Identification | Back Directory | [Name]
TIMP-2, HUMAN | [CAS]
124861-55-8 | [Synonyms]
TIMP-2 CSC-21K HUMAN TIMP-2 TIMP-2, HUMAN Hexapeptide-12 TIMP-2, HUMAN, R-DNA Human Oligopeptide-20 Proteinase inhibitor TIMP2 TIMP-2, HUMAN, RECOMBINANT TIMP-2, HUMAN。Hexapeptide-12 Tissue metalloprotease inhibitor 2 Tissue metalloproteinase inhibitor 2 TISSUE IHIBITOR OF METALLOPROTEINASE-2 TISSUE INHIBITOR OF METALLOPROTEINASE-2 Recombinant Human TIMP-2 Protein, His Tag TIMP-2, HUMAN RHEUMATOID SYNOVIAL FIBROBLAST TISSUE INHIBITOR OF METALLOPROTEINASE-2, HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2, HUMAN, R-DNA Tissue Inhibitor of Metalloproteinase-2 from mouse Tissue Inhibitor of Metalloproteinase-2 from human fibroblasts | [EINECS(EC#)]
-0 | [MDL Number]
MFCD00285923 |
Hazard Information | Back Directory | [Biological Activity]
Tissue inhibitor of metalloproteinase-2 (TIMP-2)like other protease inhibitorsfunctions as a key modulator of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act through a matrix metalloproteinase (MMP)-independent mechanism inhibiting endothelial cell proliferation in vitro. It demonstrates anti-angiogenic activities in vivo. TIMP-2 is a target gene of the microRNA-miR-22.''TIMP-2 has a greater binding efficiency to MMP-2 than the other MMPs. Although TIMP-2 is an inhibitor of MMP-2it is also required at low concentrations for the activation of MMP-2. |
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Biolab Reagents
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027-65279366 18108604356 |
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www.biolabreagent.com/ |
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