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ChemicalBook--->CAS DataBase List--->1246303-22-9

1246303-22-9

1246303-22-9 Structure

1246303-22-9 Structure
IdentificationBack Directory
[Name]

C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt)
[CAS]

1246303-22-9
[Synonyms]

C16 Ceramide-1-Phosphate (d18:1/16:0)
C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium salt)
[Molecular Formula]

C34H71N2O6P
[MDL Number]

MFCD22416608
[MOL File]

1246303-22-9.mol
[Molecular Weight]

634.911
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

Chloroform:Methanol:NH4OH (80:20:2): Soluble
[form ]

A solid
Hazard InformationBack Directory
[Description]

C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells.1 It is created by phosphorylation of C16 ceramide by ceramide kinase. C16 C1P activates cytosolic phospholipase A2α (PLA2α) and stimulates the release of arachidonic acid in A549 cells.2
[References]

1. Lamour, N.F., Stahelin, R.V., Wijesinghe, D.S., et al. Ceramide kinase uses ceramide provided by ceramide transport protein: Localization to organelles of eicosanoid synthesis J. Lipid Res. 48(6),1293-1304(2007).
2. Wijesinghe, D.S., Subramanian, P., Lamour, N.F., et al. Chain length specificity for activation of cPLA2alpha by C1P: Use of the dodecane delivery system to determine lipid-specific effects J. Lipid Res. 50(10),1986-1995(2009).
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