| Identification | Back Directory | [Name]
Acetylene-PEG5-acid | [CAS]
1245823-51-1 | [Synonyms]
1245823-51-1
Alkyne-PEG4-Acid
Alkyne-PEG5-COOH
Alkyne-PEG5-acid
Propargyl-PEG5-acid
PROPARGYL-PEG5-COOH
Acetylene-PEG5-acid
Propargyl-PEG4-C2-acid
Propyne-PEG4-CH2CH2COOH
Propargyl-PEG4-CH2CH2COOH
4,7,10,13,16-Pentaoxanonadec-18-ynoic acid
4,7,10,13,16-pentaoxanonadec-18-yn-1-oic acid | [Molecular Formula]
C14H24O7 | [MDL Number]
MFCD22201536 | [MOL File]
1245823-51-1.mol | [Molecular Weight]
304.34 |
| Chemical Properties | Back Directory | [Boiling point ]
426.3±45.0 °C(Predicted) | [density ]
1.127±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Liquid | [pka]
4.28±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
Propargyl-PEG5-acid has a propargyl group at one end and an acid group at the other end. The acid can react with primary amines to form a stable amide bond, activation will be needed. The PEG units enhances solubility of the molecule in aqueous environment. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry. | [Uses]
Alkyne-PEG5-acid may be used in the synthesis of peptide nucleic acid (PNA) oligomers that can conjugate with vitamin B12 via Cu-catalyzed 1,3-dipolar cycloaddition in order to study if vitamin B12 to transport PNA oligonucleotides into bacterial cells. | [Uses]
Propargyl-peg5 Acid is used as a reactant in the preparation of site-specific antibody-pyrrolobenzodiazepine conjugates. |
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