| Identification | Back Directory | [Name]
1H-Pyrrole-2,5-dione, 1-[4-[2-(4-Methylphenyl)-1,2-diphenylethenyl]phenyl]- | [CAS]
1245606-71-6 | [Synonyms]
TPE-MI
TPE-Thiol
1-{4-[1,2-Diphenyl-2-(p-tolyl)vinyl]phenyl}-1H-pyrrole-2,5-dione
(E)-1-(4-(1,2-diphenyl-2-p-tolylvinyl)phenyl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[4-[2-(4-Methylphenyl)-1,2-diphenylethenyl]phenyl]- | [Molecular Formula]
C31H23NO2 | [MOL File]
1245606-71-6.mol | [Molecular Weight]
441.52 |
| Hazard Information | Back Directory | [Uses]
TPE-Thiol is an aggregation-induced emission (AIE) material for the "Click" chemistry, with alkene and thio group detection. | [General Description]
Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays. | [IC 50]
Plasmodium |
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Sigma-Aldrich
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Energy Chemical
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http://www.energy-chemical.com |
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Merck KGaA
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http://www.sigmaaldrich.cn |
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