| Identification | Back Directory | [Name]
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | [CAS]
1240948-77-9 | [Synonyms]
Vonoprazan-4
Vonoprazan-027
TAK438 Impurity 19
Vonoprazan Impuirty 64
Vonoprazan Fumarate impurity B
Voronozan initiator 1 impurity J
Vonoprazan impurity SM2-I: 3-nitrile
Voronazan Fumarate Starter 1 Impurity J
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile
TAK-438( Vonoprazan fumarate) intermediate 2
1H-Pyrrole-3-carbonitrile,5-(2-fluorophenyl)-
Vonoprazan impurity 32/5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | [EINECS(EC#)]
809-912-0 | [Molecular Formula]
C11H7FN2 | [MDL Number]
MFCD24619247 | [MOL File]
1240948-77-9.mol | [Molecular Weight]
186.19 |
| Chemical Properties | Back Directory | [Boiling point ]
364.7±32.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Solid | [pka]
13.87±0.50(Predicted) | [Dielectric constant]
5.5（22.0℃） | [InChI]
InChI=1S/C11H7FN2/c12-10-4-2-1-3-9(10)11-5-8(6-13)7-14-11/h1-5,7,14H | [InChIKey]
ZDEFHFJZEDEKJO-UHFFFAOYSA-N | [SMILES]
N1C(C2=CC=CC=C2F)=CC(C#N)=C1 |
| Hazard Information | Back Directory | [Description]
5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile is an important pharmaceutical intermediate component for the preparation of vonorasan fumarate, vonoprazan key intermediate, and vorexanol fumarate intermediate. | [Uses]
5-?(2-Fluorophenyl)?-?1H-?pyrrole-?3-?carbonitrile is an impurity of Vonoprazan (V767010) a novel potassium-?competitive acid blocker for the treatment of acid-?related diseases. |
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