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ChemicalBook--->CAS DataBase List--->1229018-87-4

1229018-87-4

1229018-87-4 Structure

1229018-87-4 Structure
IdentificationBack Directory
[Name]

TPN171
[CAS]

1229018-87-4
[Synonyms]

TPN171
[Molecular Formula]

C24H35N5O3
[MDL Number]

MFCD32067974
[MOL File]

1229018-87-4.mol
[Molecular Weight]

441.57
Chemical PropertiesBack Directory
[density ]

1.20±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

8.78±0.50(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6. TPN171 is a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.
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