Identification | Back Directory | [Name]
ex229 (compound 991) | [CAS]
1219739-36-2 | [Synonyms]
EX229 EX-229 EX 229;EX229 ex229 (compound 991) AMPK Activator 991 (Compound 991) 5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid 5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl- | [Molecular Formula]
C24H18ClN3O3 | [MDL Number]
MFCD31696597 | [MOL File]
1219739-36-2.mol | [Molecular Weight]
431.87 |
Chemical Properties | Back Directory | [Boiling point ]
706.4±70.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml | [form ]
A solid | [pka]
3.40±0.25(Predicted) | [color ]
Off-white to pink |
Hazard Information | Back Directory | [Uses]
AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes. |
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