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ChemicalBook--->CAS DataBase List--->1217094-53-5

1217094-53-5

1217094-53-5 Structure

1217094-53-5 Structure
IdentificationBack Directory
[Name]

ICI-118551
[CAS]

1217094-53-5
[Synonyms]

(RS)-ICI-118551 Hydrochloride
(Rac)-ICI-118551 (hydrochloride)
3-(isopropylamino)-1-((7-methyl-2,3-dihydro-1H-inden-4-yl)oxy)butan-2-ol hydrochloride
[Molecular Formula]

C17H28ClNO2
[MDL Number]

MFCD00153812
[MOL File]

1217094-53-5.mol
[Molecular Weight]

313.863
Hazard InformationBack Directory
[Uses]

(Rac)-ICI-118551 hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac)-ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease[1].
[References]

[1] Wu Q, et, al. Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer's disease. Neural Regen Res. 2017 Sep;12(9):1499-1506. DOI:10.4103/1673-5374.215261
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