| Identification | Back Directory | [Name]
PTC-209 (hydrobroMide) | [CAS]
1217022-63-3 | [Synonyms]
CS-1314
PTC-209HBR
PTC-209 (hydrobroMide)
N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-1,3-thiazol-2-amine
2-Thiazolamine, N-(2,6-dibromo-4-methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyrimidin-3-yl)-, hydrobromide | [Molecular Formula]
C17H13Br2N5OS.HBr | [MDL Number]
MFCD28143911 | [MOL File]
1217022-63-3.mol | [Molecular Weight]
576.103 |
| Hazard Information | Back Directory | [Uses]
PTC-209 is a potent and selective BMI-1 inhibitor. It results in irreversible reduction of cancer-initiating cells (CICs). | [in vivo]
PTC-209 (60 mg/kg body weight; subcutaneously; once a day for 11 days) significantly reduces tumor volume[2]. | Animal Model: | Nude mice (male, aged 8-10 weeks, HCT1116 cell-derived tumor)[1] | | Dosage: | 60 mg/kg body weight | | Administration: | Subcutaneously; once a day for 11 days | | Result: | Significantly reduced tumor volume.
|
| [storage]
Store at -20°C |
|
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|