| Identification | Back Directory | [Name]
MT-7716 hydrochloride | [CAS]
1215859-93-0 | [Synonyms]
MT-7716 hydrochloride
W-212393 hydrochloride | [Molecular Formula]
C27H29ClN4O2 | [MDL Number]
MFCD32062656 | [MOL File]
1215859-93-0.mol | [Molecular Weight]
477.01 |
| Hazard Information | Back Directory | [Description]
MT-7716 is a Novel selective nonpeptidergic NOP receptor agonist, effectively blocking ethanol-induced increase in GABAergic transmission, decreasing spontaneous miniature inhibitory postsynaptic currents (mIPSCs) in central amygdala (CeA). | [Uses]
MT-7716 hydrochloride (W-212393 hydrochloride) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention[1]. | [IC 50]
NOP Receptor/ORL1 | [References]
[1] de Guglielmo G, et al, MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats. Addict Biol. 2015 Jul;20(4):643-51. DOI:10.1111/adb.12157 |
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
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