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ChemicalBook--->CAS DataBase List--->1206711-14-9

1206711-14-9

1206711-14-9 Structure

1206711-14-9 Structure
IdentificationBack Directory
[Name]

DMH2
[CAS]

1206711-14-9
[Synonyms]

DMH2
VU 0364849
DMH2 >=98% (HPLC)
4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
[Molecular Formula]

C27H25N5O2
[MDL Number]

MFCD29917837
[MOL File]

1206711-14-9.mol
[Molecular Weight]

451.52
Chemical PropertiesBack Directory
[density ]

1.31±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

powder
[pka]

6.27±0.10(Predicted)
[color ]

white to beige
Hazard InformationBack Directory
[Uses]

DMH 2 is a selective BMP inhibitor.
[Biological Activity]

DMH2 is a potent antagonist of the BMP receptor activin receptor-like kinase 3 (ALK3BMPR-IA) th at enhance liver regeneration. DMH2 potently inhibits BMP signaling and induced the greatest reduction of cell growth and expression of Id family members in H1299 non-small cell lung carcinoma cells.
[storage]

Store at -20°C
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