| Identification | Back Directory | [Name]
CKI-7 | [CAS]
120615-25-0 | [Synonyms]
N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide
N-(2-AMinoethyl)-5-chloro-isoquinolin-8-sulphonaMide
8-[N-(2-Aminoethyl)sulphamoyl]-5-chloroisoquinoline, CKI-7
8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro- Dihydrochloride | [Molecular Formula]
C11H12ClN3O2S | [MDL Number]
MFCD00897689 | [MOL File]
120615-25-0.mol | [Molecular Weight]
285.75 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Crystalline Solid | [Melting point ]
188-190°C | [Boiling point ]
499.7±55.0 °C(Predicted) | [density ]
1.432±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
H2O: 9 mg/mL
| [form ]
solid
| [pka]
7.80±0.50(Predicted) | [color ]
white
|
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Crystalline Solid | [Uses]
Found to have a potent inhibitory action against casein kinase 1 completely with respect to ATP and a much weaker effect on casein kinase 2 and other protein kinases | [Definition]
ChEBI: A member of the class of isoquinolines that is isoquinoline-8-sulfonamide which is substituted by chlorine at position 5 and in which the sulfonamide nitrogen is substituted by a 2-aminoethyl group. It is an inhibitor of casein kinase I. |
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