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ChemicalBook--->CAS DataBase List--->120595-72-4

120595-72-4

120595-72-4 Structure

120595-72-4 Structure
IdentificationBack Directory
[Name]

2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE
[CAS]

120595-72-4
[Synonyms]

6-Chloro-2'-deoxyguanosine
2-AMINO-6-CHLOROPURINE-2'-DEOXYRIBOSIDE
2-AMINO-6-CHLOROPURINE-2'-DEOXY-D-RIBOFURANOSIDE
2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside
2-Amino-6-chloro-9-(β-D-2-deoxyribofuranosyl)purine
2-Amino-6-chloro-9-(β-D-2-deoxyribofuranosyl) purine
2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
2-AMINO-6-CHLORO-9-(BETA-D-2-DEOXYRIBOFURANOSYL)PURINE
9H-Purin-2-amine, 6-chloro-9-(2-deoxy-β-D-erythro-pentofuranosyl)-
6-Chloro-9-(2-deoxy-β-D-erythro -pentofu ranosyl)-9H -purin-2-amine
(2R,3S,5S)-5-(2-AMino-6-chloro-9H-purin-9-yl)-2-(hydroxyMethyl)tetrahydrofuran-3-ol
[Molecular Formula]

C10H12ClN5O3
[MDL Number]

MFCD00672274
[MOL File]

120595-72-4.mol
[Molecular Weight]

285.69
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
Hazard InformationBack Directory
[Uses]

2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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