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ChemicalBook--->CAS DataBase List--->1201903-02-7

1201903-02-7

1201903-02-7 Structure

1201903-02-7 Structure
IdentificationBack Directory
[Name]

Ixazomib Impurity 1
[CAS]

1201903-02-7
[Synonyms]

Ixazomib Impurity 1
2,5-dichloro-N-(2-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-2-oxoethyl)benzamide
2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide
Benzamide, 2,5-dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-
[Molecular Formula]

C24H33BCl2N2O4
[MOL File]

1201903-02-7.mol
[Molecular Weight]

495.25
Chemical PropertiesBack Directory
[storage temp. ]

-20°C Freezer
[solubility ]

Dichloromethane; Chloroform; Methanol; Ethyl Acetate; DMSO;
[form ]

Solid
[color ]

White
Hazard InformationBack Directory
[Uses]

2,5-Dichloro-N-[2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxoethyl]-benzamide is an intermediate used in the synthesis of Ixazomib (I942000), which is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.
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