Identification | Back Directory | [Name]
MB-07133 | [CAS]
1190389-15-1 | [Synonyms]
RVT-901 KRP-114V Vibegron-13C-D4 Vibegron (MK-4618) (6S)-4,6,7,8-Tetrahydro-N-[4-[[(2S,5R)-5-[(R)-hydroxyphenylmethyl]-2-pyrrolidinyl]methyl]phenyl]-4-oxopyrrolo[1,2-a]pyrimidine-6-carboxamide Pyrrolo[1,2-a]pyrimidine-6-carboxamide, 4,6,7,8-tetrahydro-N-[4-[[(2S,5R)-5-[(R)-hydroxyphenylmethyl]-2-pyrrolidinyl]methyl]phenyl]-4-oxo-, (6S)- | [Molecular Formula]
C26H28N4O3 | [MDL Number]
MFCD28502057 | [MOL File]
1190389-15-1.mol | [Molecular Weight]
444.53 |
Chemical Properties | Back Directory | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [form ]
Solid | [pka]
13.55±0.70(Predicted) | [color ]
White to off-white | [InChIKey]
DJXRIQMCROIRCZ-XOEOCAAJSA-N | [SMILES]
C12CC[C@@H](C(NC3=CC=C(C[C@@H]4CC[C@H]([C@H](O)C5=CC=CC=C5)N4)C=C3)=O)N1C(=O)C=CN=2 |
Hazard Information | Back Directory | [Uses]
Vibegron is a potent and selective β3 Adrenergic receptor agonist for the treatment of overactive bladder. | [Definition]
ChEBI: Vibegron is a pyrrolopyrimidine obtained by formal condensation of the carboxy group of (6S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid with the amino group of (R)-[(2R,5S)-5-(4-aminobenzyl)pyrrolidin-2-yl](phenyl)methanol. It is a beta3-adrenergic receptor agonist currently in clinical development for the treatment of patients with overactive bladder. It has a role as a beta-adrenergic agonist. It is a secondary alcohol, a member of pyrrolidines, a member of benzenes, a secondary carboxamide, a pyrrolopyrimidine and a secondary amine. | [storage]
4°C, away from moisture and light |
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