Identification | Back Directory | [Name]
Triptonodiol | [CAS]
117456-87-8 | [Synonyms]
Triptonodiol 2(1H)-Phenanthrenone, 3,4,4a,9,10,10a-hexahydro-5-hydroxy-1-(hydroxymethyl)-8-methoxy-1,4a-dimethyl-7-(1-methylethyl)-, (1S,4aS,10aR)- | [Molecular Formula]
C21H30O4 | [MOL File]
117456-87-8.mol | [Molecular Weight]
346.46 |
Chemical Properties | Back Directory | [Boiling point ]
529.6±50.0 °C(Predicted) | [density ]
1.121±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.62±0.60(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2]. | [References]
[1] Zhou BN, et al. Studies on New Components and Stereochemistry of Diterpenoids from Trypterygium wilfordii. Planta Med. 1988 Aug;54(4):330-2. DOI:10.1055/s-2006-962448 [2] Feng Jin, et al. Network pharmacology?based investigation of potential targets of Triptonodiol acting on Non-Small-Cell Lung Cancer. Research Square. 2023. DOI: 10.21203/rs.3.rs-2463976/v1 |
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