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ChemicalBook--->CAS DataBase List--->1174157-65-3

1174157-65-3

1174157-65-3 Structure

1174157-65-3 Structure
IdentificationBack Directory
[Name]

Propargyl-succinimidyl-ester
[CAS]

1174157-65-3
[Synonyms]

Alkyne-NHS ester
Propargyl-NHS Ester
Propargyl-PEG1-NHS este
Propargyl-dPEG??-NHS ester
Propargyl-succinimidyl-ester
Propargyl-N-hydroxysuccinimidyl ester
N-Succinimidyl 3-(propargyloxy)propionate
2,5-Dioxopyrrolidin-1-yl 3-(prop-2-ynyloxy)propanoate
2,5-dioxopyrrolidin-1-yl 3-(prop-2-yn-1-yloxy)propanoate
3-Propargyloxy-propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
3-(2-Propyn-1-yloxy)propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
3-(2-Propyn-1-yloxy)-2,5-dioxo-1-pyrrolidinyl Ester Propanoic Acid
Propanoic acid, 3-(2-propyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester
[Molecular Formula]

C10H11NO5
[MDL Number]

MFCD13184973
[MOL File]

1174157-65-3.mol
[Molecular Weight]

225.2
Chemical PropertiesBack Directory
[Melting point ]

36-41°C
[Boiling point ]

351.2±48.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in DMSO, DCM, DMF
[form ]

Solid
[color ]

Gray
[Water Solubility ]

Slightly soluble in water.
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

29280000
Hazard InformationBack Directory
[Description]

Propargyl-PEG1-NHS ester is an amine reactive reagent that can be used for derivatizing peptides, antibodies, amine coated surfaces etc. The alkyne group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.
[Uses]

N-Succinimidyl 3-(propargyloxy)propionate is an acetylene-containing reagent with NHS ester functionality for reaction with amines.
[Uses]

Propargyl-N-hydroxysuccinimidyl ester may be used as a tool for identifying nucleophilic ligandable hotspots by chemoproteomic approaches.
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